The Thévenin Lab at Lehigh University
  • Twitter

Welcome to the Thévenin Lab

Membrane biochemistry and targeted drug delivery

The research conducted in our group lies at the interface of cell biology, chemistry, biochemistry, and biophysics, with a particular focus on problems in cancer drug delivery and membrane protein cell signaling. As such, our work is applied, fundamental, and highly interdisciplinary. Current research programs are organized around two main areas:

  • Developing novel strategies to specifically target and deliver  therapeutics to cancer cells and tumors.

  • Understanding how oligomerization affects membrane receptors activity and cell signaling.

More specifically, we are interested in the role of the transmembrane and juxtamembrane domains in this process. As such, our work is applied, fundamental, highly interdisciplinary, and draws upon areas such as peptide and protein chemistry, biochemistry, biophysics, molecular, cellular and structural biology, cell signaling, and oncology.

Ongoing projects are aimed at targeting and delivering potent cytotoxics and antimicrobial peptides to cancer cells using the pH(Low) Insertion Peptide, and at identifying the structural requirements for the dimerization of an understudied, but essential family of membrane receptors, the receptor protein-tyrosine phosphatases (RPTPs).

  • Learn More

Menu

  • Homepage
  • Research
  • The Group
    • Members
    • Group Photos
    • Other Photos
  • Publications
  • News

Get in touch

Don't hesitate to contact us. There are always openings for motivated undergraduate and graduate students. Please, email for more information about availability and specific research projects.

  • damien.thevenin@lehigh.edu
  • (610) 758-2886 (D. Thévenin)
    (610) 758-4969 (Lab)
  • Department of Chemistry
    Lehigh University
    Seeley Mudd Building
    6 E. Packer Avenue
    Bethlehem, PA 18015

Design: Damien Thévenin and HTML5 UP. Photos: Christa Neu. Illustration: Antti Uotila.