The Thévenin Lab

Membrane Protein Biophysics: Transduction and Modulation of Receptor Signaling

Membrane Biophysics & Drug Delivery

Dec 2015
Oct 2015
Sep 2015
Aug 2015
Mar 2015
Jul 2014
Jun 2014
Mar 2014
Nov 2013
Sep 2013
Jun 2013
May 2013
Jan 2013
May 2012
Jan 2012
Oct 2011
Sep 2011
Aug 2011

NIH-NCI Grant on Receptor Protein-Tyrosine Phosphatases

Our lab was awarded an NIH-NCI R21 grant to determine how a receptor protein tyrosine phosphatase physically interacts with itself and with the epidermal growth factor receptor, and how these interactions affect EGFR tyrosine phosphorylation.

pHLIP research covered by Lehigh News

A Cancer Research Team Hits Its Target:
http://www1.lehigh.edu/news/cancer-research-team-hits-its-target

Kelly has published her 2nd article!

Kelly’s second papers has just been accepted for publication in the Biochemical Journal. Congratulations to Kelly!
Down-Regulation of PAR1 Activity with a pHLIP-based Allosteric Antagonist Induces Cancer Cell Death

Congratulations to Janessa

Janessa has successfully defended her Ph.D. Thesis Proposal, and she is now a Ph.D. candidate!

First Article From the Lab!

The first manuscript form our lab has just been accepted in Molecular Pharmaceutics!! Congratulations to Kelly!
Inhibition of Cancer Cell Proliferation and Breast Tumor Targeting of pHLIP-monomethyl Auristatin E Conjugates

Congratulations to Betty

Betty has successfully defended her Ph.D. Thesis Proposal, and she is now a Ph.D. candidate!

First NIH-NCI Grant!

Our lab was awarded an NIH-NCI R21 grant to develop and validate the pH(Low) insertion peptide (pHLIP) as a novel therapeutic for prostate cancer.

Lehigh Research Grant

The lab has received a 2014 Lehigh University FRG for the project: “Role of the transmembrane regions in the interaction between Receptor Protein-Tyrosine Phosphatases and Receptor Tyrosine Kinase”.

New lab member - Janessa Gerhart

We are really excited to welcome Janessa Gerhart in our group. Janessa is currently a first year graduate study in the Department of Chemistry. Welcome!

Congratulations to Kelly

Kelly has successfully defended her Ph.D. Thesis Proposal, and she is now a Ph.D. candidate!