CHM 456 SPECTRAL ANALYSIS (Spring
2004)
Goal:
To explain how to how find review papers about MALDI-MS ("matrix-assisted laser desorption ionization-mass spectrometry") and papers about *specific* applications of MALDI-MS to a chemical, clinical, or pharmaceutical problem.
For this purpose, please start with Web of Science ("WOS") or SciFinder Scholar ("SFS"). If you are off-campus, you may find WOS easier to access (details later) than SFS. If you have trouble finding what you need using one of these, try the "Other Science Databases" identified below.
TABLE OF CONTENTS
Web of Science
SciFinder Scholar 2004
Other Science Databases
Obtaining Copies of Papers
Contact Information For Further Assistance
WHAT IT IS
A library database that lets you:
1. search for literature about a given subject, 1993-forward
2. start with a known paper (can be pre-1993) and find papers 1993 and later
that cite it.
ACCESS
Web of Science (hereafter, WOS) is available off the library listing of databases. Select on-campus or off-campus depending on where you are. If you are off-campus, you will be prompted for your Lehigh login and ID.
FINDING REVIEW PAPERS
When you are new to a field, it helps to begin by finding "review" papers that give you an overview of a field. By virtue of being "reviews", these papers can lead you to other papers.
To find articles that provide a "review" perspective of aspects of MALDI, go to WOS. Click Full Search. Deselect the other dbases: just use the Science Citation Index. Click on general search. Enter your search term string: in this case, try putting in: maldi or matrix-assisted laser desorption ionization. After putting in the search string, select "review" at the place where it says to "set search limits".
The screen should look like this:
Notice that we've put in both "maldi" and the full phrase "matrix-assisted
laser desorption ionization". Also, we did not put in "maldi-ms".
Searching the acronym 'maldi' picks up everything that would be picked up by
'maldi-ms'.
Now click on "search". A list of titles comes up containing review articles. A portion of the list appears as follows:
Scroll through these to find one that of interest to you. Click on ones that
interest you to see their full WOS record. An example of a record that comes
up in this search is:
This is *not* the full text of an article; it provides information *about* an article, including an abstract. How do you get to the full text of the article?
Click on the link (partially clipped in above screen shot) that looks like
this: 
This will bring up the SFX interface, which will (in this case) let you access the full text of the article. If you are off-campus, you will need to set up the proxy server to access journal articles.
In this case, the full text is available electronically. If you find, using SFX, that it is not available electronically, then off the SFX screen you can access ASA, Lehigh's online catalog, to see if it is available in print at Lehigh. (For further information about obtaining articles, see below).
Note: if you have gotten to this point and *not* found what you need, you may also the following search string, which uses some 'advanced' features: the truncator * and the operator "same": maldi or matrix assis* same mass spectrom* . Click on WOS's context-sensitive help documentation for details and examples. If you still have difficulties, please contact the science librarian any time for assistance. Contact information is provided below.
FINDING ADDITIONAL PAPERS
If you decide that you are interested in the general topic covered by the paper you just brought up (analysis of proteins and proteomes), how can you find additional papers about this topic? Suppose that you're also interested in limiting the results to a specific time, say for example 2002-2004.
There are a few techniques to find papers that satisfy these criteria.
(i.)
One method is to go back to the Annual Review of Biochemistry paper above, which is from 2001, and click on the links for "times cited". This will let you find items published later in time that cite the paper. This is a great way to locate a group of papers that deal with the same subject matter. (If you have no date restrictions, you can also click on "cited references" to find earlier papers).
(ii.)
You can also do a date restriction to the period 2002-2004, as follows:
Then, click on the "general search" button. Redo your search, but this time add a concept that focuses the search, such as "protein". Also, don't restrict your search this time to "review.
So the search screen should look like this:
(iii) Yet another method to bring up papers about the particular
topic you are interested in: when you find an item you like, click on
the following button, which appears in records like the one above: 
OTHER SEARCH TECHNIQUES FOR THE UNDAUNTED
Finally, supposing you already know that an author is an important one for the field you are searching, you can type in the author's name in the author search area of the general search screen. OR, if you already know a good paper (including ones that you found using another database), you can use the cited reference search capabilities of WOS. Click on Full Search, then on Cited Reference Search.
SciFinder Scholar allows you to access a number of databases, including (most importantly) Chemical Abstracts, and MedLine (see below for other ways to access MedLine).
Persons off-campus may find it significantly easier to use WOS.
Whether you are on or off-campus, see here
for information about accessing SciFinder Scholar 2004.
If you want to learn more about SciFinder Scholar, see CAS
webpage about SciFinder Scholar.
Tips:
NOTE: DO NOT USE SCIFINDER SCHOLAR FOR COMMERCIAL PURPOSES.
SciFinder Scholar and Science Citation Index are only two of the databases that Lehigh's libraries make available. Some other databases to check are these (click onthe link brings you details about the database):
(1.) If you have done a search on one of Lehigh's databases, look for a link to SFX. If you are off-campus, you will need to set up the proxy server to access journal articles.
(2.) Check ASA to see if Lehigh has the journal, either in paper or electronic format. (Also, check to see if there is a full text linkage from the bibliographic database you search.)
(3.) You may want to see if one of the regional libraries has the journal. For this purpose, you can also check WorldCat.
(4.) You may order the article through interlibrary loan. Use this form. An additional way to find papers: browse the tables of contents of recent issues or archived (bound) copies in the library, or look for relevant electronic journals browsable here by title or linked on ASA.
(5.) The above concerns papers. Requests for books can be done via interlibrary loan or by using the PALCI service.
Special notes about document delivery for distance learning/off-campus students:
At any point in your research, email the Science Librarian, Brian Simboli, if you have any questions. You may also call him at x5003 or drop by his office at Room 633 in Fairchild-Martindale Library. On Tuesday afternoons he is usually in the consulting office behind the help desk on the first floor of the library.