A-to-I RNA editing website homepage

Publications (chronologically)

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Agranat, L., Raitskin, O., Sperling, J., and Sperling, R. (2008). The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus. Proc Natl Acad Sci U S A 105, 5028-5033.

Cenci, C., Barzotti, R., Galeano, F., Corbelli, S., Rota, R., Massimi, L., Di Rocco, C., O'Connell, M.A., and Gallo, A. (2008). Down-regulation of RNA editing in pediatric astrocytomas: ADAR2 EDITING ACTIVITY INHIBITS CELL MIGRATION AND PROLIFERATION. J Biol Chem 283, 7251-7260.

Luo, M., and Schramm, V.L. (2008). Transition state structure of E. coli tRNA-specific adenosine deaminase. J Am Chem Soc 130, 2649-2655.

Nishimoto, Y., Yamashita, T., Hideyama, T., Tsuji, S., Suzuki, N., and Kwak, S. (2008). Determination of editors at the novel A-to-I editing positions. Neurosci Res.

Tian, N., Wu, X., Zhang, Y., and Jin, Y. (2008). A-to-I editing sites are a genomically encoded G: implications for the evolutionary significance and identification of novel editing sites. RNA 14, 211-216.

Beal, P.A., Maydanovych, O., and Pokharel, S. (2007). The chemistry and biology of RNA editing by adenosine deaminases. Nucleic Acids Symp Ser (Oxf), 83-84.

Das, A.K., and Carmichael, G.G. (2007). ADAR editing wobbles the microRNA world. ACS Chem Biol 2, 217-220.

Habig, J.W., Dale, T., and Bass, B.L. (2007). miRNA editing--we should have inosine this coming. Mol Cell 25, 792-793.

Hou, Y., Chen, J., Gao, M., Zhou, F., Du, W., Shen, Y., Yang, S., and Zhang, X. J. (2007). Five novel mutations of RNA-specific adenosine deaminase gene with dyschromatosis symmetrica hereditaria. Acta Derm Venereol 87, 18-21.

Jepson, J.E., and Reenan, R.A. (2007). Genetic approaches to studying adenosine-to-inosine RNA editing. Methods Enzymol 424, 265-287.

Kawahara, Y., Zinshteyn, B., Sethupathy, P., Iizasa, H., Hatzigeorgiou, A. G., and Nishikura, K. (2007). Redirection of silencing targets by adenosine-to-inosine editing of miRNAs. Science 315, 1137-1140.

Keegan, L.P., Rosenthal, J.J., Roberson, L.M., and O'Connell, M.A. (2007). Purification and assay of ADAR activity. Methods Enzymol 424, 301-317.

Laxminarayana, D., Khan, I.U., O'Rourke, K.S., and Giri, B. (2007). Induction of 150-kDa adenosine deaminase that acts on RNA (ADAR)-1 gene expression in normal T lymphocytes by anti-CD3-epsilon and anti-CD28. Immunology 122, 623-633.

Laxminarayana, D., O'Rourke K, S., Maas, S., and Olorenshaw, I. (2007). Altered editing in RNA editing adenosine deaminase ADAR2 gene transcripts of systemic lupus erythematosus T lymphocytes. Immunology.

Lev-Maor, G., Sorek, R., Levanon, E.Y., Paz, N., Eisenberg, E., and Ast, G. (2007). RNA-editing-mediated exon evolution. Genome Biol 8, R29.

Liang, H., and Landweber, L. F. (2007). Hypothesis: RNA editing of microRNA target sites in humans? Rna 13, 463-467.

Nie, Y., Hammond, G. L., and Yang, J. H. (2007). Double-stranded RNA deaminase ADAR1 increases host susceptibility to virus infection. J Virol 81, 917-923.

Olsen, D. P., Dunlap, K., and Jacob, M. H. (2007). Kainate receptors and RNA editing in cholinergic neurons. J Neurochem 101, 327-341.

Ohlson, J., Pedersen, J.S., Haussler, D., and Ohman, M. (2007). Editing modifies the GABA(A) receptor subunit alpha3. RNA 13, 698-703.

Ohman, M. (2007). A-to-I editing challenger or ally to the microRNA process. Biochimie 89, 1171-1176.

Paz, N., Levanon, E.Y., Amariglio, N., Heimberger, A.B., Ram, Z., Constantini, S., Barbash, Z.S., Adamsky, K., Safran, M., Hirschberg, A., et al. (2007). Altered adenosine-to-inosine RNA editing in human cancer. Genome Res 17, 1586-1595.

Rula, E.Y., and Emeson, R.B. (2007). Mouse models to elucidate the functional roles of adenosine-to-inosine editing. Methods Enzymol 424, 333-367.

Schoft, V.K., Schopoff, S., and Jantsch, M.F. (2007). Regulation of glutamate receptor B pre-mRNA splicing by RNA editing. Nucleic Acids Res 35, 3723-3732.

Sergeeva, O.A., Amberger, B.T., and Haas, H.L. (2007). Editing of AMPA and serotonin 2C receptors in individual central neurons, controlling wakefulness. Cell Mol Neurobiol 27, 669-680.

Sixsmith, J., and Reenan, R.A. (2007). Comparative genomic and bioinformatic approaches for the identification of new adenosine-to-inosine substrates. Methods Enzymol 424, 245-264.

Valente, L., and Nishikura, K. (2007). RNA binding-independent dimerization of adenosine deaminases acting on RNA and dominant negative effects of nonfunctional subunits on dimer functions. J Biol Chem 282, 16054-16061.

Zahn, R. C., Schelp, I., Utermohlen, O., and von Laer, D. (2007). A-to-G hypermutation in the genome of lymphocytic choriomeningitis virus. J Virol 81, 457-464.

Zhang, F., and Rabinovici, R. (2007). Adenosine deaminase acting on RNA 1 accelerates cell cycle through increased translation and activity of cyclin-dependent kinase 2. Shock 27, 214-219.

Blow, M. J., Grocock, R. J., van Dongen, S., Enright, A. J., Dicks, E., Futreal, P. A., Wooster, R., and Stratton, M. R. (2006). RNA editing of human microRNAs. Genome Biol 7, R27.

Casey, J. L. (2006). RNA editing in hepatitis delta virus. Curr Top Microbiol Immunol 307, 67-89.

Chilibeck, K. A., Wu, T., Liang, C., Schellenberg, M. J., Gesner, E. M., Lynch, J. M., and MacMillan, A. M. (2006). FRET analysis of in vivo dimerization by RNA-editing enzymes. J Biol Chem 281, 16530-16535.

Diegelmann, S., Nieratschker, V., Werner, U., Hoppe, J., Zars, T., and Buchner, E. (2006). The conserved protein kinase-A target motif in synapsin of Drosophila is effectively modified by pre-mRNA editing. BMC Neurosci 7, 76.

Du, Y., Davisson, M. T., Kafadar, K., and Gardiner, K. (2006). A-to-I pre-mRNA editing of the serotonin 2C receptor: comparisons among inbred mouse strains. Gene 382, 39-46.

Feng, Y., Sansam, C. L., Singh, M., and Emeson, R. B. (2006). Altered RNA editing in mice lacking ADAR2 autoregulation. Mol Cell Biol 26, 480-488.

Gan, Z., Zhao, L., Yang, L., Huang, P., Zhao, F., Li, W., and Liu, Y. (2006). RNA editing by ADAR2 is metabolically regulated in pancreatic islets and beta-cells. J Biol Chem 281, 33386-33394.

Gardiner, K., and Du, Y. (2006). A-to-I editing of the 5HT2C receptor and behaviour. Brief Funct Genomic Proteomic 5, 37-42.

Greger, I. H., Akamine, P., Khatri, L., and Ziff, E. B. (2006). Developmentally regulated, combinatorial RNA processing modulates AMPA receptor biogenesis. Neuron 51, 85-97.

Guryev, V., Koudijs, M. J., Berezikov, E., Johnson, S. L., Plasterk, R. H., van Eeden, F. J., and Cuppen, E. (2006). Genetic variation in the zebrafish. Genome Res 16, 491-497.

Hallegger, M., Taschner, A., and Jantsch, M. F. (2006). RNA aptamers binding the double-stranded RNA-binding domain. Rna 12, 1993-2004.

Hartwig, D., Schutte, C., Warnecke, J., Dorn, I., Hennig, H., Kirchner, H., and Schlenke, P. (2006). The large form of ADAR 1 is responsible for enhanced hepatitis delta virus RNA editing in interferon-alpha-stimulated host cells. J Viral Hepat 13, 150-157.

Hoopengardner, B. (2006). Adenosine-to-inosine RNA editing: perspectives and predictions. Mini Rev Med Chem 6, 1213-1216.

Kawahara, Y., and Nishikura, K. (2006). Extensive adenosine-to-inosine editing detected in Alu repeats of antisense RNAs reveals scarcity of sense-antisense duplex formation. FEBS Lett 580, 2301-2305.

Kittler, J. T. (2006). Censoring the editor in transient forebrain ischemia. Neuron 49, 646-648.

Laurencikiene, J., Kallman, A. M., Fong, N., Bentley, D. L., and Ohman, M. (2006). RNA editing and alternative splicing: the importance of co-transcriptional coordination. EMBO Rep 7, 303-307.

Levanon, E. Y., and Eisenberg, E. (2006). Algorithmic approaches for identification of RNA editing sites. Brief Funct Genomic Proteomic 5, 43-45.

Maas, S., Kawahara, Y., Tamburro, K. M., and Nishikura, K. (2006). A-to-I RNA Editing and Human Disease. RNA Biol 3.

Maydanovych, O., and Beal, P. A. (2006). C6-substituted analogues of 8-azanebularine: probes of an RNA-editing enzyme active site. Org Lett 8, 3753-3756.

Neeman, Y., Levanon, E. Y., Jantsch, M. F., and Eisenberg, E. (2006). RNA editing level in the mouse is determined by the genomic repeat repertoire. Rna 12, 1802-1809.

Nishikura, K. (2006). Editor meets silencer: crosstalk between RNA editing and RNA interference. Nat Rev Mol Cell Biol 7, 919-931.

O'Connell, M. A., and Keegan, L. P. (2006). Drosha versus ADAR: wrangling over pri-miRNA. Nat Struct Mol Biol 13, 3-4.

Peng, P. L., Zhong, X., Tu, W., Soundarapandian, M. M., Molner, P., Zhu, D., Lau, L., Liu, S., Liu, F., and Lu, Y. (2006). ADAR2-dependent RNA editing of AMPA receptor subunit GluR2 determines vulnerability of neurons in forebrain ischemia. Neuron 49, 719-733.

Pokharel, S., and Beal, P. A. (2006). High-throughput screening for functional adenosine to inosine RNA editing systems. ACS Chem Biol 1, 761-765.

Poulsen, H., Jorgensen, R., Heding, A., Nielsen, F. C., Bonven, B., and Egebjerg, J. (2006). Dimerization of ADAR2 is mediated by the double-stranded RNA binding domain. Rna 12, 1350-1360.

Roberson, L. M., and Rosenthal, J. J. (2006). An accurate fluorescent assay for quantifying the extent of RNA editing. Rna 12, 1907-1912.

Rubio, M. A., Ragone, F. L., Gaston, K. W., Ibba, M., and Alfonzo, J. D. (2006). C to U editing stimulates A to I editing in the anticodon loop of a cytoplasmic threonyl tRNA in Trypanosoma brucei. J Biol Chem 281, 115-120.

Stapleton, M., Carlson, J. W., and Celniker, S. E. (2006). RNA editing in Drosophila melanogaster: New targets and functional consequences. Rna 12, 1922-1932.

Steele, E. J., Lindley, R. A., Wen, J., and Weiller, G. F. (2006). Computational analyses show A-to-G mutations correlate with nascent mRNA hairpins at somatic hypermutation hotspots. DNA Repair (Amst) 5, 1346-1363.

Stefl, R., Xu, M., Skrisovska, L., Emeson, R. B., and Allain, F. H. (2006). Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs. Structure 14, 345-355.

Takahashi, M., Yoshimoto, T., Shimoda, M., Kono, T., Koizumi, M., Yazumi, S., Shimada, Y., Doi, R., Chiba, T., and Kubo, H. (2006). Loss of function of the candidate tumor suppressor prox1 by RNA mutation in human cancer cells. Neoplasia 8, 1003-1010.

Tojo, K., Sekijima, Y., Suzuki, T., Suzuki, N., Tomita, Y., Yoshida, K., Hashimoto, T., and Ikeda, S. (2006). Dystonia, mental deterioration, and dyschromatosis symmetrica hereditaria in a family with ADAR1 mutation. Mov Disord 21, 1510-1513.

Wang, H., Hou, Z., Wu, Y., Ma, X., and Luo, X. (2006). p150 ADAR1 isoform involved in maintenance of HeLa cell proliferation. BMC Cancer 6, 282.

Xu, M., Wells, K. S., and Emeson, R. B. (2006). Substrate-dependent contribution of double-stranded RNA-binding motifs to ADAR2 function. Mol Biol Cell 17, 3211-3220.

Yang, W., Chendrimada, T. P., Wang, Q., Higuchi, M., Seeburg, P. H., Shiekhattar, R., and Nishikura, K. (2006). Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat Struct Mol Biol 13, 13-21.

Agrawal, R., and Stormo, G. D. (2005). Editing efficiency of a Drosophila gene correlates with a distant splice site selection. Rna 11, 563-566.

Clutterbuck, D. R., Leroy, A., O'Connell, M. A., and Semple, C. A. (2005). A bioinformatic screen for novel A-I RNA editing sites reveals recoding editing in BC10. Bioinformatics 21, 2590-2595.

Eisenberg, E., Adamsky, K., Cohen, L., Amariglio, N., Hirshberg, A., Rechavi, G., and Levanon, E. Y. (2005). Identification of RNA editing sites in the SNP database. Nucleic Acids Res 33, 4612-4617.

Eisenberg, E., Nemzer, S., Kinar, Y., Sorek, R., Rechavi, G., and Levanon, E. Y. (2005). Is abundant A-to-I RNA editing primate-specific? Trends Genet 21, 77-81.

Elias, Y., and Huang, R. H. (2005). Biochemical and structural studies of A-to-I editing by tRNA:A34 deaminases at the wobble position of transfer RNA. Biochemistry 44, 12057-12065.

George, C. X., Wagner, M. V., and Samuel, C. E. (2005). Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing. J Biol Chem 280, 15020-15028.

Jones, A. K., Grauso, M., and Sattelle, D. B. (2005). The nicotinic acetylcholine receptor gene family of the malaria mosquito, Anopheles gambiae. Genomics 85, 176-187.

Koeris, M., Funke, L., Shrestha, J., Rich, A., and Maas, S. (2005). Modulation of ADAR1 editing activity by Z-RNA in vitro. Nucleic Acids Res 33, 5362-5370.

Kwak, S., and Kawahara, Y. (2005). Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis. J Mol Med 83, 110-120.

Levanon, E. Y., Hallegger, M., Kinar, Y., Shemesh, R., Djinovic-Carugo, K., Rechavi, G., Jantsch, M. F., and Eisenberg, E. (2005). Evolutionarily conserved human targets of adenosine to inosine RNA editing. Nucleic Acids Res 33, 1162-1168.

Levanon, K., Eisenberg, E., Rechavi, G., and Levanon, E. Y. (2005). Letter from the editor: Adenosine-to-inosine RNA editing in Alu repeats in the human genome. EMBO Rep 6, 831-835.

Macbeth, M. R., Schubert, H. L., Vandemark, A. P., Lingam, A. T., Hill, C. P., and Bass, B. L. (2005). Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing. Science 309, 1534-1539.

Mattick, J. S., and Makunin, I. V. (2005). Small regulatory RNAs in mammals. Hum Mol Genet 14 Spec No 1, R121-132.

Nie, Y., Ding, L., Kao, P. N., Braun, R., and Yang, J. H. (2005). ADAR1 interacts with NF90 through double-stranded RNA and regulates NF90-mediated gene expression independently of RNA editing. Mol Cell Biol 25, 6956-6963.

Ohlson, J., Enstero, M., Sjoberg, B. M., and Ohman, M. (2005). A method to find tissue-specific novel sites of selective adenosine deamination. Nucleic Acids Res 33, e167.

Pfeffer, S., Sewer, A., Lagos-Quintana, M., Sheridan, R., Sander, C., Grasser, F. A., van Dyk, L. F., Ho, C. K., Shuman, S., Chien, M., et al. (2005). Identification of microRNAs of the herpesvirus family. Nat Methods 2, 269-276.

Reenan, R. A. (2005). Molecular determinants and guided evolution of species-specific RNA editing. Nature 434, 409-413.

Sallacz, N. B., and Jantsch, M. F. (2005). Chromosomal storage of the RNA-editing enzyme ADAR1 in Xenopus oocytes. Mol Biol Cell 16, 3377-3386.

Sattelle, D. B., Jones, A. K., Sattelle, B. M., Matsuda, K., Reenan, R., and Biggin, P. C. (2005). Edit, cut and paste in the nicotinic acetylcholine receptor gene family of Drosophila melanogaster. Bioessays 27, 366-376.

Valente, L., and Nishikura, K. (2005). ADAR gene family and A-to-I RNA editing: diverse roles in posttranscriptional gene regulation. Prog Nucleic Acid Res Mol Biol 79, 299-338.

Vitali, P., Basyuk, E., Le Meur, E., Bertrand, E., Muscatelli, F., Cavaille, J., and Huttenhofer, A. (2005). ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs. J Cell Biol 169, 745-753.

Wang, Q., Zhang, Z., Blackwell, K., and Carmichael, G. G. (2005). Vigilins bind to promiscuously A-to-I-edited RNAs and are involved in the formation of heterochromatin. Curr Biol 15, 384-391.

Xia, S., Yang, J., Su, Y., Qian, J., Ma, E., and Haddad, G. G. (2005). Identification of new targets of Drosophila pre-mRNA adenosine deaminase. Physiol Genomics 20, 195-202.

Yang, W., Wang, Q., Howell, K. L., Lee, J. T., Cho, D. S., Murray, J. M., and Nishikura, K. (2005). ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells. J Biol Chem 280, 3946-3953.

Zheng, Z. M., Tang, S., and Tao, M. (2005). Development of resistance to RNAi in mammalian cells. Ann N Y Acad Sci 1058, 105-118.

Amore, M., Strippoli, P., Laterza, C., Tagariello, P., Vitale, L., Casadei, R., Frabetti, F., Canaider, S., Lenzi, L., D'Addabbo, P., et al. (2004). Sequence analysis of ADARB1 gene in patients with familial bipolar disorder. J Affect Disord 81, 79-85.

Bezanilla, F. (2004). RNA editing of a human potassium channel modifies its inactivation. Nat Struct Mol Biol 11, 915-916.

Bhalla, T., Rosenthal, J. J., Holmgren, M., and Reenan, R. (2004). Control of human potassium channel inactivation by editing of a small mRNA hairpin. Nat Struct Mol Biol 11, 950-956.

Blow, M., Futreal, P. A., Wooster, R., and Stratton, M. R. (2004). A survey of RNA editing in human brain. Genome Res 14, 2379-2387.

Bundschuh, R. (2004). Computational prediction of RNA editing sites. Bioinformatics 20, 3214-3220.

Dawson, T. R., Sansam, C. L., and Emeson, R. B. (2004). Structure and sequence determinants required for the RNA editing of ADAR2 substrates. J Biol Chem 279, 4941-4951.

Flomen, R., Knight, J., Sham, P., Kerwin, R., and Makoff, A. (2004). Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene. Nucleic Acids Res 32, 2113-2122.

Hartner, J. C., Schmittwolf, C., Kispert, A., Muller, A. M., Higuchi, M., and Seeburg, P. H. (2004). Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1. J Biol Chem 279, 4894-4902.

Haudenschild, B. L., Maydanovych, O., Veliz, E. A., Macbeth, M. R., Bass, B. L., and Beal, P. A. (2004). A transition state analogue for an RNA-editing reaction. J Am Chem Soc 126, 11213-11219.

Jayan, G. C. (2004). RNA editing in hepatitis delta virus: unsolved puzzles. ScientificWorldJournal 4, 628-637.

Johnston, N. (2004). Abundant A-to-I editing in the human transcriptome. Drug Discov Today 9, 822-823.

Kawahara, Y., Ito, K., Sun, H., Ito, M., Kanazawa, I., and Kwak, S. (2004). Regulation of glutamate receptor RNA editing and ADAR mRNA expression in developing human normal and Down's syndrome brains. Brain Res Dev Brain Res 148, 151-155.

Keegan, L. P., Leroy, A., Sproul, D., and O'Connell, M. A. (2004). Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes. Genome Biol 5, 209.

Kim, D. D., Kim, T. T., Walsh, T., Kobayashi, Y., Matise, T. C., Buyske, S., and Gabriel, A. (2004). Widespread RNA editing of embedded alu elements in the human transcriptome. Genome Res 14, 1719-1725.

Koslowsky, D. J. (2004). A historical perspective on RNA editing: how the peculiar and bizarre became mainstream. Methods Mol Biol 265, 161-197.

Levanon, E. Y., Eisenberg, E., Yelin, R., Nemzer, S., Hallegger, M., Shemesh, R., Fligelman, Z. Y., Shoshan, A., Pollock, S. R., Sztybel, D., et al. (2004). Systematic identification of abundant A-to-I editing sites in the human transcriptome. Nat Biotechnol 22, 1001-1005.

Luciano, D. J., Mirsky, H., Vendetti, N. J., and Maas, S. (2004). RNA editing of a miRNA precursor. Rna 10, 1174-1177.

Macbeth, M. R., Lingam, A. T., and Bass, B. L. (2004). Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding. Rna 10, 1563-1571.

McGrew, L., Price, R. D., Hackler, E., Chang, M. S., and Sanders-Bush, E. (2004). RNA editing of the human serotonin 5-HT2C receptor disrupts transactivation of the small G-protein RhoA. Mol Pharmacol 65, 252-256.

Morse, D. P. (2004). Identification of substrates for adenosine deaminases that act on RNA. Methods Mol Biol 265, 199-218.

Nishikura, K. (2004). Editing the message from A to I. Nat Biotechnol 22, 962-963.

Song, W., Liu, Z., Tan, J., Nomura, Y., and Dong, K. (2004). RNA editing generates tissue-specific sodium channels with distinct gating properties. J Biol Chem 279, 32554-32561.

Stephens, O. M., Haudenschild, B. L., and Beal, P. A. (2004). The binding selectivity of ADAR2's dsRBMs contributes to RNA-editing selectivity. Chem Biol 11, 1239-1250.

Tohda, M., Sukma, M., and Watanabe, H. (2004). RNA editing and short variant of serotonin 2C receptor mRNA in neuronally differentiated NG108-15 cells. J Pharmacol Sci 96, 164-169.

Wang, Q., Miyakoda, M., Yang, W., Khillan, J., Stachura, D. L., Weiss, M. J., and Nishikura, K. (2004). Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene. J Biol Chem 279, 4952-4961.

Xie, K., Sowden, M. P., Dance, G. S., Torelli, A. T., Smith, H. C., and Wedekind, J. E. (2004). The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1. Proc Natl Acad Sci U S A 101, 8114-8119.

Yang, W., Wang, Q., Kanes, S. J., Murray, J. M., and Nishikura, K. (2004). Altered RNA editing of serotonin 5-HT2C receptor induced by interferon: implications for depression associated with cytokine therapy. Brain Res Mol Brain Res 124, 70-78.

Zhang, Z., and Carmichael, G. G. (2004). Methods for the analysis of adenosine-to-inosine editing in RNA. Methods Mol Biol 257, 75-84.

Barbon, A., Vallini, I., La Via, L., Marchina, E., and Barlati, S. (2003). Glutamate receptor RNA editing: a molecular analysis of GluR2, GluR5 and GluR6 in human brain tissues and in NT2 cells following in vitro neural differentiation. Brain Res Mol Brain Res 117, 168-178.

Bratt, E., and Ohman, M. (2003). Coordination of editing and splicing of glutamate receptor pre-mRNA. Rna 9, 309-318.

Carlson, C. B., Stephens, O. M., and Beal, P. A. (2003). Recognition of double-stranded RNA by proteins and small molecules. Biopolymers 70, 86-102.

Cho, D. S., Yang, W., Lee, J. T., Shiekhattar, R., Murray, J. M., and Nishikura, K. (2003). Requirement of dimerization for RNA editing activity of adenosine deaminases acting on RNA. J Biol Chem 278, 17093-17102.

Desterro, J. M., Keegan, L. P., Lafarga, M., Berciano, M. T., O'Connell, M., and Carmo-Fonseca, M. (2003). Dynamic association of RNA-editing enzymes with the nucleolus. J Cell Sci 116, 1805-1818.

Doyle, M., and Jantsch, M. F. (2003). Distinct in vivo roles for double-stranded RNA-binding domains of the Xenopus RNA-editing enzyme ADAR1 in chromosomal targeting. J Cell Biol 161, 309-319.

Dracheva, S., Elhakem, S. L., Marcus, S. M., Siever, L. J., McGurk, S. R., and Haroutunian, V. (2003). RNA editing and alternative splicing of human serotonin 2C receptor in schizophrenia. J Neurochem 87, 1402-1412.

Gallo, A., Keegan, L. P., Ring, G. M., and O'Connell, M. A. (2003). An ADAR that edits transcripts encoding ion channel subunits functions as a dimer. Embo J 22, 3421-3430.

Greger, I. H., Khatri, L., Kong, X., and Ziff, E. B. (2003). AMPA receptor tetramerization is mediated by Q/R editing. Neuron 40, 763-774.

Hoopengardner, B., Bhalla, T., Staber, C., and Reenan, R. (2003). Nervous system targets of RNA editing identified by comparative genomics. Science 301, 832-836.

Kallman, A. M., Sahlin, M., and Ohman, M. (2003). ADAR2 A-->I editing: site selectivity and editing efficiency are separate events. Nucleic Acids Res 31, 4874-4881.

Kawahara, Y., Ito, K., Sun, H., Kanazawa, I., and Kwak, S. (2003). Low editing efficiency of GluR2 mRNA is associated with a low relative abundance of ADAR2 mRNA in white matter of normal human brain. Eur J Neurosci 18, 23-33.

Klaue, Y., Kallman, A. M., Bonin, M., Nellen, W., and Ohman, M. (2003). Biochemical analysis and scanning force microscopy reveal productive and nonproductive ADAR2 binding to RNA substrates. Rna 9, 839-846.

Lincecum, T. L., Jr., Tukalo, M., Yaremchuk, A., Mursinna, R. S., Williams, A. M., Sproat, B. S., Van Den Eynde, W., Link, A., Van Calenbergh, S., Grotli, M., et al. (2003). Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase. Mol Cell 11, 951-963.

Maas, S., Rich, A., and Nishikura, K. (2003). A-to-I RNA editing: recent news and residual mysteries. J Biol Chem 278, 1391-1394.

Markle, D., Das, S., Ward, S. V., and Samuel, C. E. (2003). Functional analysis of the KCS-like element of the interferon-inducible RNA-specific adenosine deaminase ADAR1 promoter. Gene 304, 143-149.

Sansam, C. L., Wells, K. S., and Emeson, R. B. (2003). Modulation of RNA editing by functional nucleolar sequestration of ADAR2. Proc Natl Acad Sci U S A 100, 14018-14023.

Saunders, L. R., and Barber, G. N. (2003). The dsRNA binding protein family: critical roles, diverse cellular functions. Faseb J 17, 961-983.

Seeburg, P. H., and Hartner, J. (2003). Regulation of ion channel/neurotransmitter receptor function by RNA editing. Curr Opin Neurobiol 13, 279-283.

Tonkin, L. A., and Bass, B. L. (2003). Mutations in RNAi rescue aberrant chemotaxis of ADAR mutants. Science 302, 1725.

Veliz, E. A., Easterwood, L. M., and Beal, P. A. (2003). Substrate analogues for an RNA-editing adenosine deaminase: mechanistic investigation and inhibitor design. J Am Chem Soc 125, 10867-10876.

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	last updated May 2008 by Stefan Maas & Nicole Perry